Acute Traumatic Coagulopathy in Severe Trauma Patients
Journal of the Korean Society of Traumatology
; : 72-78, 2012.
Article
em Ko
| WPRIM
| ID: wpr-176218
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Clinical observation and research findings show that acute traumatic coagulopathy (ATC) is a major factor that must be addressed in the early care of severe trauma patients. ATC is associated with increased transfusion requirements and poor clinical outcomes. This study aimed to correlate the early predictable factors of ATC with the outcomes in severe trauma patients.METHODS:
Retrospective data from the trauma registry on severe trauma patients (Injury Severity Score (ISS)> or =16) were used to identify variables independently associated with coagulopathy. Univariate associations were calculated, and a multivariable logistic regression analysis was used to determine variables independently associated with ATC.RESULTS:
Patients were mostly male, aged 51.9+/-17.8 years, with an injury severity score of 24.1+/-12.4. ATC, as diagnosed in the emergency department (ED), occurred in 17% of the severe trauma patients. Using a multivariable logistic regression analysis, early predictable variables independently associated with ATC were base deficit (odds ratio (OR) 13.03; 95% confidence interval (CI) 3.47-48.93), acute liver injury (OR 4.24; 95% CI 1.06-17.00), and transfer from another hospital (OR 21.00; 95% CI 3.23-136.60).CONCLUSION:
ATC is associated with mortality in severe trauma patients, and some variables associated with trauma and shock are an independent predictors of ATC. These variables contribute to the early recognition and management of coagulopathy, which may improve the outcome from trauma resuscitation.Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Ressuscitação
/
Choque
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Escala de Gravidade do Ferimento
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Modelos Logísticos
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Estudos Retrospectivos
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Emergências
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Fígado
Tipo de estudo:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Humans
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Male
Idioma:
Ko
Revista:
Journal of the Korean Society of Traumatology
Ano de publicação:
2012
Tipo de documento:
Article