A Case of Multiple Myeloma with Biclonal (IgG-K and IgA-K) M-proteins / 대한임상병리학회지
Korean Journal of Clinical Pathology
; : 310-314, 1998.
Article
em Ko
| WPRIM
| ID: wpr-177889
Biblioteca responsável:
WPRO
ABSTRACT
Two M-protein peaks in serum protein electrophoresis are rarely present in patients with plasma cell discrasia. We describe a 72-year-old male patient with multiple myeloma secreting biclonal M-proteins, which were confirmed by immunofixation. Immunoelectrophoresis has some difficulties to dectect M components when a very small amount of M-protein develops an equivocally abnormal precipitation arc. In this case, serum protein electrophoresis revealed two M peaks, one in beta and the other in gamma globulin region. An immunoelectrophoresis revealed unequivocally abnormal precipitation arcs in IgA and K light chain regions, but the arc in IgG region was equivocal. We performed an immunofixation and confirmed biclonal gammopathy, IgA-K and IgG-K types. This result supports the view that immunofixation is an useful confirmatory test when immunoelectrophoresis results are equivocal.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Plasmócitos
/
Gama-Globulinas
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Imunoglobulina A
/
Imunoglobulina G
/
Proteínas do Mieloma
/
Imunoeletroforese
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Eletroforese
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Mieloma Múltiplo
Limite:
Aged
/
Humans
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Male
Idioma:
Ko
Revista:
Korean Journal of Clinical Pathology
Ano de publicação:
1998
Tipo de documento:
Article