Allopurinol-induced DRESS syndrome mimicking biliary obstruction
Clinical and Molecular Hepatology
; : 71-75, 2014.
Article
em En
| WPRIM
| ID: wpr-18373
Biblioteca responsável:
WPRO
ABSTRACT
An 84-year-old man was admitted to our hospital with fever, jaundice, and itching. He had been diagnosed previously with chronic renal failure and diabetes, and had been taking allopurinol medication for 2 months. A physical examination revealed that he had a fever (38.8degrees C), jaundice, and a generalized maculopapular rash. Azotemia, eosinophilia, atypical lymphocytosis, elevation of liver enzymes, and hyperbilirubinemia were detected by blood analysis. Magnetic resonance cholangiography revealed multiple cysts similar to choledochal cysts in the liver along the biliary tree. Obstructive jaundice was suspected clinically, and so an endoscopic ultrasound examination was performed, which ruled out a diagnosis of obstructive jaundice. The patient was diagnosed with DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome due to allopurinol. Allopurinol treatment was stopped and steroid treatment was started. The patient died from cardiac arrest on day 15 following admission.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Sistema Biliar
/
Bilirrubina
/
Doenças Biliares
/
Tomografia Computadorizada por Raios X
/
Alopurinol
/
Angiografia por Ressonância Magnética
/
Endossonografia
/
Creatina
/
Eosinófilos
/
Síndrome de Hipersensibilidade a Medicamentos
Limite:
Aged
/
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
Clinical and Molecular Hepatology
Ano de publicação:
2014
Tipo de documento:
Article