Flecainide-Induced Torsade de Pointes Successfully Treated with Intensive Pharmacological Therapy
International Journal of Arrhythmia
; : 97-102, 2016.
Article
em En
| WPRIM
| ID: wpr-186466
Biblioteca responsável:
WPRO
ABSTRACT
Flecainide acetate is a potent class IC anti-arrhythmic drug with a major sodium channel blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse. It may also result in life-threatening arrhythmia, although cases of flecainide-induced torsades de pointes are rare. Furthermore, the electrical and hemodynamic deteriorations observed during flecainide toxicity may not respond to conventional treatments. In the present study, we report the case of a 20-year-old Korean man with flecainide poisoning, who presented with hypotension. The patient was successfully treated with sodium bicarbonate, amiodarone, MgSO₄, and lidocaine, with no recourse to extracorporeal therapy. Although there is no standard therapy for flecainide toxicity, this report demonstrates that intensive pharmacological treatment is beneficial in cases of flecainide overdose.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Intoxicação
/
Arritmias Cardíacas
/
Choque
/
Canais de Sódio
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Torsades de Pointes
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Flecainida
/
Bicarbonato de Sódio
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Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
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Amiodarona
/
Hemodinâmica
Limite:
Humans
Idioma:
En
Revista:
International Journal of Arrhythmia
Ano de publicação:
2016
Tipo de documento:
Article