Successful Treatment of Interstitial Pneumonitis Induced by Leflunomide / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
; : 268-273, 2007.
Article
em Ko
| WPRIM
| ID: wpr-196275
Biblioteca responsável:
WPRO
ABSTRACT
Leflunomide is a disease-modifying antirheumatic drug that has been available in Korea since 2003. Leflunomide induced interstitial pneumonitis has been reported as an adverse effect in other countries but not in Korea. A 57-year-old woman was treated with leflunomide since she had been resistant to methotrexate, hydroxychloroquine and sulfasalazine. She developed high fever, dyspnea, and non-productive cough 3 months after the administration of leflunomide. She was diagnosed leflunomide-induced interstitial pneumonitis based on history, physical, laboratory, radiologic and pathologic findings. The patient was treated by prednisolone 1 mg/kg/day with cholestyramine 24 g/day, resulting in dramatic improvement. Here we report a case of leflunomide induced pneumonitis treated successfully with high dose steroid.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Pneumonia
/
Artrite Reumatoide
/
Sulfassalazina
/
Prednisolona
/
Metotrexato
/
Resina de Colestiramina
/
Doenças Pulmonares Intersticiais
/
Tosse
/
Dispneia
/
Febre
Limite:
Female
/
Humans
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
The Journal of the Korean Rheumatism Association
Ano de publicação:
2007
Tipo de documento:
Article