Repeated spurious elevation of serum prostate-specific antigen values solved by chemiluminescence analysis: A possible interference by heterophilic antibodies
Korean Journal of Urology
; : 785-787, 2015.
Article
em En
| WPRIM
| ID: wpr-198008
Biblioteca responsável:
WPRO
ABSTRACT
Heterophilic antibodies are human immunoglobulins directed against various animal antigens. They can produce false-positive results in the analysis of different tumor markers, including prostate-specific antigen. This interference can lead to misdiagnosis, unnecessary tests, and overtreatment in some cases. We present herein the case of a 52-year-old man with repeated spurious elevation of prostate-specific antigen, reaching levels of 108.7 ng/mL, that were suspected to be caused by heterophilic antibodies. The interference was solved by changing the analysis technique. Real values of prostate-specific antigen were less than 1 ng/mL.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Neoplasias da Próstata
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Anticorpos Heterófilos
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Antígeno Prostático Específico
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Luminescência
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Reações Falso-Positivas
Limite:
Humans
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Male
Idioma:
En
Revista:
Korean Journal of Urology
Ano de publicação:
2015
Tipo de documento:
Article