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Comparison of the Clinical Outcomes of Red Blood Cell Transfusion in Cardiac Surgical Patients according to the Hematocrit / 대한수혈학회지
Article em Ko | WPRIM | ID: wpr-199578
Biblioteca responsável: WPRO
ABSTRACT
BACKGROUND: Recent studies have shown that blood transfusions, and especially red blood cells, are associated with potential adverse outcomes. This study was designed to investigate the effects of red blood cell transfusion according to the hematocrit on the clinical outcomes after cardiac surgery. METHODS: The 433 patients who were undergoing cardiac surgery were randomized to two groups. One group was transfused red blood cells with a hematocrit of 20%, and the other group was transfused red blood cells with a hematocrit of 20~25%. The amounts of intraoperative and postoperative transfusion and various parameters of the clinical outcomes were checked. RESULTS: In the hematocrit 20% group, and the postoperative hemoglobin and hematocrit were lower than that of the hematocrit >20% group. But there were no differences of the amounts of intraoperative and postoperative transfusion, the use of inotropics, the platelet count, the prothrombin time (PT), the activated partial thromboplastin time (aPTT), the levels of aspartate aminotransferase (AST), the levels of alanine aminotransferase (ALT), blood urea nitrogen (BUN), serum creatinine (Cr), brain natriuretic peptide (BNP) and creatine kinase MB (CK-MB), the extubation time and the ICU stay time between the two groups. CONCLUSION: A hematocrit lower than 20% was tolerated by the cardiac surgical patients and it was not related to the postoperative morbidity and outcomes.
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Texto completo: 1 Índice: WPRIM Assunto principal: Tempo de Tromboplastina Parcial / Contagem de Plaquetas / Tempo de Protrombina / Aspartato Aminotransferases / Cirurgia Torácica / Transfusão de Sangue / Nitrogênio da Ureia Sanguínea / Hemoglobinas / Transfusão de Eritrócitos / Peptídeo Natriurético Encefálico Tipo de estudo: Clinical_trials Limite: Humans Idioma: Ko Revista: Korean Journal of Blood Transfusion Ano de publicação: 2010 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Tempo de Tromboplastina Parcial / Contagem de Plaquetas / Tempo de Protrombina / Aspartato Aminotransferases / Cirurgia Torácica / Transfusão de Sangue / Nitrogênio da Ureia Sanguínea / Hemoglobinas / Transfusão de Eritrócitos / Peptídeo Natriurético Encefálico Tipo de estudo: Clinical_trials Limite: Humans Idioma: Ko Revista: Korean Journal of Blood Transfusion Ano de publicação: 2010 Tipo de documento: Article