Fertility sparing surgery in early stage epithelial ovarian cancer / 부인종양
Journal of Gynecologic Oncology
; : 320-327, 2014.
Article
em En
| WPRIM
| ID: wpr-202218
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
Fertility sparing surgery (FSS) is a strategy often considered in young patients with early epithelial ovarian cancer. We investigated the role and the outcomes of FSS in eEOC patients who underwent comprehensive surgery.METHODS:
From January 2003 to January 2011, 24 patients underwent fertility sparing surgery. Eighteen were one-to-one matched and balanced for stage, histologic type and grading with a group of patients who underwent radical comprehensive staging (n=18). Demographics, surgical procedures, morbidities, pathologic findings, recurrence-rate, pregnancy-rate and correlations with disease-free survival were assessed.RESULTS:
A total of 36 patients had a complete surgical staging including lymphadenectomy and were therefore analyzed. Seven patients experienced a recurrence four (22%) in the fertility sparing surgery group and three (16%) in the control group (p=not significant). Sites of recurrence were residual ovary (two), abdominal wall and peritoneal carcinomatosis in the fertility sparing surgery group; pelvic (two) and abdominal wall in the control group. Recurrences in the fertility sparing surgery group appeared earlier (mean, 10.3 months) than in radical comprehensive staging group (mean, 53.3 months) p<0.001. Disease-free survival were comparable between the two groups (p=0.422). No deaths were reported. All the patients in fertility sparing surgery group recovered a regular period. Thirteen out of 18 (72.2%) attempted to have a pregnancy. Five (38%) achieved a spontaneous pregnancy with a full term delivery.CONCLUSION:
Fertility sparing surgery in early epithelial ovarian cancer submitted to a comprehensive surgical staging could be considered safe with oncological results comparable to radical surgery group.Palavras-chave
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Índice:
WPRIM
Assunto principal:
Neoplasias Ovarianas
/
Resultado da Gravidez
/
Análise de Sobrevida
/
Estudos Retrospectivos
/
Resultado do Tratamento
/
Neoplasias Epiteliais e Glandulares
/
Fertilidade
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Preservação da Fertilidade
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Infertilidade Feminina
/
Excisão de Linfonodo
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Journal of Gynecologic Oncology
Ano de publicação:
2014
Tipo de documento:
Article