Therapeutic Experience of Bing-Neel Syndrome Associated with Waldenstrom's Macroglobulinemia
Journal of Korean Medical Science
; : 1079-1081, 2007.
Article
em En
| WPRIM
| ID: wpr-204035
Biblioteca responsável:
WPRO
ABSTRACT
Waldenstrom's macroglobulinemia is an uncommon low-grade B-cell lymphoproliferative disorder in which monoclonal immunoglobulin M is produced. Neurological symptoms due to hyperviscosity are frequent manifestations of Waldenstrom's macroglobulinemia. However, central nervous system infiltration by plasmacytoid lymphocytes (Bing-Neel syndrome) has only rarely been reported. We report a case of a 51-yr-old woman suffering from Waldenstrom's macroglobulinemia who complained of persistant headache. Brain magnetic resonance imaging revealed an extra-axial soft tissue mass along the left cavernous sinus, left tentorium, right tentorium, and falx cerebri. A stereotactic biopsy of dural tissue from the falx was performed and showed plasmacytoid lymphocyte infiltration. The patient became symptom- free with irradiation of the whole brain followed by chemotherapy with fludarabine.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Síndrome
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Vidarabina
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Encéfalo
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Doenças do Sistema Nervoso Central
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Irradiação Craniana
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Macroglobulinemia de Waldenstrom
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Anticorpos Monoclonais
Limite:
Female
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Humans
Idioma:
En
Revista:
Journal of Korean Medical Science
Ano de publicação:
2007
Tipo de documento:
Article