Behcet's Disease: The First Mongolian Case in Literature Showing HLA B51, MICA Gene Type *5/*6
Yonsei Medical Journal
; : 935-938, 2003.
Article
em En
| WPRIM
| ID: wpr-205350
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WPRO
ABSTRACT
Behcet's disease is a chronic multi-systemic disease of unknown origin that includes mucocutaneous, ocular, cardiac, vascular, renal, gastrointestinal, neurologic and cutaneous involvement. The disease is spread throughout the world, but it is most prevalent in the eastern Mediterranean region-along the Silk Road-, and in Japan, China, and Korea. Recently, we treated a Mongolian patient who had complete-type Behcet's disease. As far as we know, this case is the first report of a Mongolian with Behcet's disease in the English literature. HLA typing in this patient revealed A2, A24; B51, B35; Cw4, Cw7; DR9, DR11. Study of the MICA genetype showed *5, *6 positive. Our data provided adequate evidence, from an epidemiological aspect, to support the belief that Behcet's disease is most prevalent along the old Silk Road.
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Texto completo:
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Índice:
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Assunto principal:
Antígenos de Histocompatibilidade Classe I
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Antígenos HLA-B
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Síndrome de Behçet
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Alelos
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Genótipo
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Yonsei Medical Journal
Ano de publicação:
2003
Tipo de documento:
Article