A case of oral desensitization for hypersensitivity to exogenous progesterone
Allergy, Asthma & Respiratory Disease
; : 294-297, 2017.
Article
em Ko
| WPRIM
| ID: wpr-209998
Biblioteca responsável:
WPRO
ABSTRACT
Hypersensitivity reaction to progesterone is a rare pathologic condition which consists of autoimmune response to endogenous progesterone, known as autoimmune progesterone dermatitis, and hypersensitivity reaction to exogenous progestogen. We report the case of a 31-year-old woman with a history of whole body urticaria during exogenous progesterone supplementation for in vitro fertilization (IVF). She was admitted to the hospital for the diagnosis and management of progestogen hypersensitivity. An intradermal test with progesterone revealed positivity to 5 mg/mL of progesterone. For her next IVF, progesterone desensitization was performed in a method combining oral and intramuscular progesterone administration. After successfully achieving a target dose of 100 mg per day, the route of progesterone administration was converted to intravaginal tablet (90 mg twice a day) without any hypersensitivity reactions.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Progesterona
/
Urticária
/
Testes Intradérmicos
/
Fertilização in vitro
/
Autoimunidade
/
Dessensibilização Imunológica
/
Dermatite
/
Diagnóstico
/
Hipersensibilidade a Drogas
/
Hipersensibilidade
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
Ko
Revista:
Allergy, Asthma & Respiratory Disease
Ano de publicação:
2017
Tipo de documento:
Article