A Case of Myxedema Coma with Severe Hypoventilation / 대한내분비학회지
Journal of Korean Society of Endocrinology
; : 203-208, 2004.
Article
em Ko
| WPRIM
| ID: wpr-21314
Biblioteca responsável:
WPRO
ABSTRACT
A myxedema coma, representing the extreme feature of hypothyroidism is rare. Despite early vigorous treatment, a myxedema coma is associated with a mortality rate as high as 60%. Herein, a case of a myxedema coma, with severe hypoventilation, is described. When the patient arrived at the emergency room, she complained of dyspnea and general weakness, and was of a drowsy mental status. 7 days after admission, she was more confused and disoriented, and respiratory insufficiency had developed. Although levothyroxine was continued and her respiration improved, she still had a confused mentality and seizure developed. Despite medication her consciousness did not improve, so was discharged in despair by her family members. The respiratory abnormality with a myxedema coma is a depressed ventilatory response to hypercapnea, resulting in a decrease in alveolar ventilation, with progressive CO2 retention. An upper airway obstruction, especially during sleep, and neuromuscular dysfunction in breathing may be shown in hypothyroidism. Therefore, a myxedema coma, accompanied by severe hypoventilation, should be intensively treated with thyroid hormone replacement therapy and mechanical ventilatory support
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Respiração
/
Insuficiência Respiratória
/
Convulsões
/
Glândula Tireoide
/
Tiroxina
/
Ventilação
/
Mortalidade
/
Coma
/
Estado de Consciência
/
Terapia de Reposição Hormonal
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Ko
Revista:
Journal of Korean Society of Endocrinology
Ano de publicação:
2004
Tipo de documento:
Article