Disseminated Penicilliosis in a Korean Human Immunodeficiency Virus Infected Patient from Laos
Journal of Korean Medical Science
; : 697-700, 2012.
Article
em En
| WPRIM
| ID: wpr-21958
Biblioteca responsável:
WPRO
ABSTRACT
Penicillium marneffei may cause life-threatening systemic fungal infection in immune-compromised patients and it is endemic in Southeast Asia. A 39-yr-old HIV-infected male, living in Laos, presented with fever, cough, and facial vesiculopapular lesions, which had been apparent for two weeks. CT scans showed bilateral micronodules on both lungs; Pneumocystis jirovecii was identified by bronchoscopic biopsy. Despite trimethoprim-sulfamethoxazole and anti-tuberculosis medications, the lung lesions progressed and the facial lesions revealed central umbilications. Biopsy of the skin lesions confirmed disseminated penicilliosis, with the culture showing P. marneffei hyphae and spores. The P. marneffei was identified by rRNA PCR. A review of the bronchoscopic biopsy indicated penicilliosis. The patient completely recovered after being prescribed amphotericin-B and receiving antiretroviral therapy. This is the first case of penicilliosis in a Korean HIV-infected patient. It is necessary to consider P. marneffei when immunocompromised patients, with a history of visits to endemic areas, reveal respiratory disease.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Penicillium
/
Broncoscopia
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Tomografia Computadorizada por Raios X
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Infecções por HIV
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Anfotericina B
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Hospedeiro Imunocomprometido
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Fármacos Anti-HIV
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Pneumocystis carinii
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Dermatomicoses
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Laos
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
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Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Journal of Korean Medical Science
Ano de publicação:
2012
Tipo de documento:
Article