Effect of Initial Empirical Antibiotics Duration on Neonatal Outcomes in Very Low Birth Weight Infants / 대한주산의학회잡지
Korean Journal of Perinatology
; : 69-75, 2012.
Article
em Ko
| WPRIM
| ID: wpr-226174
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Little is known about the duration of antibiotics for suspected early-onset sepsis (EOS) with negative blood cultures. The purpose of this study is to identify associations between the duration of empirical antibiotics and neonatal outcomes.METHODS:
We retrospectively reviewed medical records of very low birth weight infants (VLBW) who admitted to NICU in 2007-2010. We defined empirical antibiotic therapy group as those who started antibiotic therapy in first 3 postnatal days. We compared the neonatal outcomes between short empirical antibiotic therapy ( or =5 days).RESULTS:
Of 122 VLBW, 72 infants were long empirical antibiotic therapy group. In the long empirical antibiotic therapy group, there were lower birth weight, higher rate of out-born, higher rate of vaginal delivery, and had lower Apgar scores. Prolonged antibiotic therapy was associated with delayed start of enteral feeding and incidence of ESBL.CONCLUSION:
Prolonged antibiotic therapy may be associated with some adverse neonatal outcomes. Therefore, wide spread agreement regarding the short empirical antibiotic therapy was needed.Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Peso ao Nascer
/
Prontuários Médicos
/
Incidência
/
Estudos Retrospectivos
/
Nutrição Enteral
/
Sepse
/
Recém-Nascido de muito Baixo Peso
/
Antibacterianos
Tipo de estudo:
Incidence_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Humans
/
Infant
Idioma:
Ko
Revista:
Korean Journal of Perinatology
Ano de publicação:
2012
Tipo de documento:
Article