Your browser doesn't support javascript.
loading
Regulatory effects of Bmi-1 gene on self-renewal of hematopoietic stem cells--review / 中国实验血液学杂志
Article em Zh | WPRIM | ID: wpr-233578
Biblioteca responsável: WPRO
ABSTRACT
Self-renewal of hematopoietic stem cells is vital for the sustained daily production of blood cells. The Bmi-1 gene is a putative oncogene belonging to the Polycomb group family. Recent studies have shown that the Polycomb-group gene Bmi-1 is indispensable for regulation of self-renewal of normal and leukemic stem cells. The research progress on structure and function of Bmi-1 gene, and its role in self-renewal of hematopoietic stem cells was reviewed.
Assuntos
Texto completo: 1 Índice: WPRIM Assunto principal: Fisiologia / Proteínas Repressoras / Células-Tronco Hematopoéticas / Proteínas Nucleares / Diferenciação Celular / Divisão Celular / Proteínas Proto-Oncogênicas / Biologia Celular / Complexo Repressor Polycomb 1 / Genética Limite: Humans Idioma: Zh Revista: Journal of Experimental Hematology Ano de publicação: 2006 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Fisiologia / Proteínas Repressoras / Células-Tronco Hematopoéticas / Proteínas Nucleares / Diferenciação Celular / Divisão Celular / Proteínas Proto-Oncogênicas / Biologia Celular / Complexo Repressor Polycomb 1 / Genética Limite: Humans Idioma: Zh Revista: Journal of Experimental Hematology Ano de publicação: 2006 Tipo de documento: Article