Evaluation of the reliability of three different hepatitis E diagnosis reagents on the clinical acute hepatitis E / 中华肝脏病杂志
Chinese Journal of Hepatology
; (12): 16-17, 2004.
Article
em Zh
| WPRIM
| ID: wpr-240523
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the reliability of different hepatitis E diagnosis reagent tests on the acute hepatitis E.</p><p><b>METHODS</b>Three acute hepatitis E diagnosis tests, E2-IgM (Wantai, China), GL-IgM and GL-IgG (Genelabs, Singapore) were compared for their reliability in a sera panel composed by 273 healthy individuals and 525 hepatitis.</p><p><b>RESULTS</b>The specificity of E2-IgM on the diagnosis of acute hepatitis E was 100.0%, it was significantly higher than GL-IgM (96.7%) and GL-IgG (85.4%). The sensitivity of E2-IgM and GL-IgG were 97.9% and 93.8% respectively, both significantly higher than GL-IgM (72.9%). Among 65 acute hepatitis cases being positive on GL-IgM test but negative on E2-IgM, 58 (89.2%) cases were found to be positive with anti-hepatitis A virus IgM, it indicated that the GL-IgM test might be interfered by other IgM antibodies on serum.</p><p><b>CONCLUSION</b>E2-IgM is a good test for the diagnosis of acute hepatitis E.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Kit de Reagentes para Diagnóstico
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Sangue
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Imunoglobulina G
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Imunoglobulina M
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Anticorpos Anti-Hepatite
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Doença Aguda
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Sensibilidade e Especificidade
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Hepatite E
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Diagnóstico
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Hepatology
Ano de publicação:
2004
Tipo de documento:
Article