Isolation and structure identification of C-25 epimers of inokosterone from Achyranthes bidentata Blume / 药学学报
Acta Pharmaceutica Sinica
; (12): 913-916, 2004.
Article
em Zh
| WPRIM
| ID: wpr-241412
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>AIM</b>To isolate C-25 epimers of inokosterone from Achyranthes bidentata Blume. and identify their structures.</p><p><b>METHODS</b>To separate C-25 epimers of inokosterone by using various kinds of chromatography methods and identify their structures on basis of spectral analysis and chemical method.</p><p><b>RESULTS</b>Three compounds were isolated and their structures were established as 25S-inokosterone (1), 25R-inokosterone (2) and ecdysterone (3).</p><p><b>CONCLUSION</b>Compounds 1 and 2 are new C-25 configuration isomers from Achyranthes bidentata Blume., their absolute configurations are elucidated at the first time, and their 13CNMR data are reported for the first time.</p>
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Índice:
WPRIM
Assunto principal:
Plantas Medicinais
/
Estereoisomerismo
/
Estrutura Molecular
/
Química
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Colestenos
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Raízes de Plantas
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Achyranthes
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Ecdisterona
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2004
Tipo de documento:
Article