Research on bitter components from Coptis chinensis based on electronic tongue / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3326-3329, 2014.
Article
em Zh
| WPRIM
| ID: wpr-244571
Biblioteca responsável:
WPRO
ABSTRACT
Isolated alkaloids from Coptis chinensis Franch. The compounds were identified as berberine, columbamine, groenlandicine, jatrorrhizine, magnoflorine, corydaldine and ferulic acid methylester. Then measured their bitter degree based on the electronic tongue and evaluated the antibacterial. The results based on the Electronic Tongue showed that berberine, columbamine, groenlandicine and jatrorrhizine have higher bitter degree than magnoflorine and corydaldine. And they also appeared better antibacterial activity on E. coli and S. aureus. The correlation coefficients between bitter degree and the two bacteria antibacterial activity were 0.983 and 0.911. So there was close relationship between the bitter degree and antibacterial activity of bitter components. Thus, it is confirmed further that bitter components are the material foundation of medicinal effectiveness of bitter herbs.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Aporfinas
/
Farmacologia
/
Staphylococcus aureus
/
Paladar
/
Berberina
/
Alcaloides de Berberina
/
Medicamentos de Ervas Chinesas
/
Testes de Sensibilidade Microbiana
/
Química
/
Reprodutibilidade dos Testes
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2014
Tipo de documento:
Article