Chemical constituents of aerial parts of Gelsemium elegans / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1305-1310, 2011.
Article
em Zh
| WPRIM
| ID: wpr-252920
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ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents from the aerial parts of Gelsemium elegans.</p><p><b>METHOD</b>Compounds were isolated and purified by repeated column chromatography, as well as semiprep arative HPLC, and their structures were identified by physicochemical properties and spectroscopic methods, such as NMR and MS.</p><p><b>RESULT</b>Sixteen compounds were obtained and identified from G. elegans, including nine alkaloids koumine (1), gelsenicine (2), 19-(Z)-akuammidine (3), gelsemoxonine(4), gelsemin (5), gelsevirine (6), humantenine (7), 11-methoxygelsemamide (8) and gelegamine D (9). Three megastigmane glycosides (3R, 5S, 6S, 7E, 9R)-megastigman-7-ene-3, 5, 6, 9-tetrol-9-O-beta-D-glucopyranoside (10), (6R, 7E, 9R)-9-hydroxy-4, 7-megastigmadien-3-one-9-O-[alpha-L-arabinopyranosyl-(1 --> 6)-beta-D-glucopyranoside] (11) and (6S, 7E, 9R) -6, 9-dihydroxy-4, 7-megastigmadien-3-one-9-O-[alpha-L-arabinopyranosyl-(1 --> 6) -beta-D-glucopyranoside] (12). Two flavone C-glycosides orientin (13) and isorientin (14); one iridoid glycoside, sweroside (15) and one fructoside, n-butyl-alpha-D-fructofuranoside (16).</p><p><b>CONCLUSION</b>Compounds 10-16 were isolated from the genus Gelsemium for the first time.</p>
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Assunto principal:
Espectrometria de Massas
/
Medicamentos de Ervas Chinesas
/
Química
/
Cromatografia Líquida de Alta Pressão
/
Gelsemium
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Componentes Aéreos da Planta
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2011
Tipo de documento:
Article