Expression and significance of P311 and ITGB4BP in non-small cell lung cancer / 中华肿瘤杂志
Chinese Journal of Oncology
; (12): 526-528, 2010.
Article
em Zh
| WPRIM
| ID: wpr-260361
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>The aim of this study was to investigate the expression and significance of P311 and ITGB4BP in non-small cell lung cancer (NSCLC).</p><p><b>METHODS</b>Tissue microarrays were prepared from 80 NSCLC specimens and examined by immunohistochemistry.</p><p><b>RESULTS</b>The positive rates of P311 and ITGB4BP expression were 77.5% (62/80) and 82.5% (66/80), respectively. The double positive expression rate was 73.8% (59/80). The consistency rate was 87.5%, and there was a significant consistency between P311 and ITGB4BP expressions (Kappa = 0.611, P < 0.001).</p><p><b>CONCLUSION</b>There may be a new signaling pathway P311-ITGB4BP in NSCLC, and it may regulate the lung cancer cell migration.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Imuno-Histoquímica
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Carcinoma de Células Escamosas
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Adenocarcinoma
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Transdução de Sinais
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Inclusão em Parafina
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Proteínas Oncogênicas
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Carcinoma Pulmonar de Células não Pequenas
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Fatores de Iniciação em Eucariotos
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Análise Serial de Tecidos
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Neoplasias Pulmonares
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Oncology
Ano de publicação:
2010
Tipo de documento:
Article