90d Exposure to Nonylphenol has Adverse Effects on the Spermatogenesis and Sperm Maturation of Adult Male Rats / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 907-911, 2014.
Article
em En
| WPRIM
| ID: wpr-264637
Biblioteca responsável:
WPRO
ABSTRACT
This study was conducted to elucidate the reproductive effect of NP on testis, epididymis and epididymal sperm in vivo. Adult male Sprague-Dawley rats were gavaged with NP at 0, 40, 100, or 250 mg/kg body weight (bw) on alternate days for 90 d. The results showed that oral administration of NP may damage the structure and function of testis, induce apoptosis and oxidative stress in epididymis or even have cytotoxic effects on epididymal sperm.
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Índice:
WPRIM
Assunto principal:
Patologia
/
Fenóis
/
Motilidade dos Espermatozoides
/
Espermatogênese
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Espermatozoides
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Testículo
/
Testosterona
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Sangue
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Administração Oral
/
Ratos Sprague-Dawley
Limite:
Animals
Idioma:
En
Revista:
Biomedical and Environmental Sciences
Ano de publicação:
2014
Tipo de documento:
Article