Risk factors of post-asphyxial multiple organ dysfunction in neonates / 中国当代儿科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the risk factors related to post-asphyxial multiple organ dysfunction (PA-MOD) in neonates.</p><p><b>METHODS</b>A total of 397 neonates with birth asphyxia were enrolled from January 2009 to December 2010.The patients were divided into PA-MOD group (n=179) and non-PA-MOD group (n=218). The risk factors of PA-MOD were retrospectively studied.</p><p><b>RESULTS</b>Multivariate logistic regression analysis showed that severe asphyxia, fetal distress, abnormal labor, and decreased amniotic fluid were the risk factors for PA-MOD among the neonates. Spearman rank correlation analysis showed that the number of the involved organs increased along with the increase of age at admission (P<0.05) and with the decrease of gestational age and birth weight (P<0.05).</p><p><b>CONCLUSIONS</b>The efforts should be made to enhance perinatal care for neonates, especially for preterm infants and low-birh-weight infants, to decrease the incidence of MOD.</p>