Effect of premenopausal hysterectomy on ovarian function / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the influence of premenopausal hysterectomy on the function of the conserved ovaries.</p><p><b>METHODS</b>A retrospective survey was conducted by sending questionnaire to 521 cases of hysterectomized women (with the conservation one or two ovaries) for benign gynecological diseases and 1,600 cases of normal controls (with contact uterus and bilateral ovaries). Age, type of operation, diagnosis and the time of the onset of the menopausal syndrome were asked in the questionnaire.</p><p><b>RESULTS</b>The mean age of the onset of the hot flush (293 cases) in the hysterectomized group was (44.64 +/- 4.31) years, which was significantly lower than that of the normal group [(46.87 +/- 4.22) years, 197 cases] (P < 0.01). The mean age of the above 293 women undergoing hysterectomized was (42.84 +/- 4.37) years. The range of the operation was positively correlated with the time of the onset of the menopause syndrome. So there was only (1.99 +/- 2.40)-year interval between the hysterectomy and the onset of the hot flush.</p><p><b>CONCLUSION</b>Hysterectomy with the conservation of bilateral/unilateral ovaries may have some certain influence on ovarian function.</p>