Expression of GIRK4 gene in kidney tissues of obese rat / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 36-39, 2013.
Article
em Zh
| WPRIM
| ID: wpr-284308
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the expression of GIRK4 gene in the kidney tissues of obese rats.</p><p><b>METHODS</b>Obese rat models were established using diet-induced method. The GIRK4 protein expression in kidney tissues was determined in 20 obese rats and 10 normal rats using Western blot analysis.</p><p><b>RESULTS</b>The relative expression level of GIRK4 protein in the kidney tissues of obese rat (1.75±0.42) was significantly lower than that in normal rats (3.37±0.68, P<0.05).</p><p><b>CONCLUSION</b>GIRK4 has a low protein expression in the kidney tissues of obese rat.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Expressão Gênica
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Canais de Potássio Corretores do Fluxo de Internalização
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Genética
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Rim
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Metabolismo
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Obesidade
Limite:
Animals
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2013
Tipo de documento:
Article