Effects of volatile oil of Rhizoma zingiberis and other two kinds of volatile oil on percutaneous penetration of bullatine A via hairless mouse skin in vitro / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 513-516, 2008.
Article
em Zh
| WPRIM
| ID: wpr-284455
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WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of volatile oils of Rhizoma Acori Tatarinowii (RAT), Semen Myristicae (SM) and Pericarpium Citri Reticulatae (PCR) on percutaneous penetration of bullatine A via hairless mouse skin in vitro.</p><p><b>METHOD</b>By an improved Franz diffusion, the effects of three kinds of volatile oils on the percutaneous penetration of bullatine A were observed and compared with Azone, and the cumulative amount of bullatine A was determined by HPLC.</p><p><b>RESULT</b>The penetration enhancement ratios of bullatine A with 7% volatile oil RAT and SM, 5% volatile oil of PCR and 3% Azone were 6.52, 6.74, 2.18, 6.03, respectively.</p><p><b>CONCLUSION</b>The volatile oil of RAT, SM and PCR enhance permeation of bullatine A, effectively.</p>
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Índice:
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Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Pele
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Absorção Cutânea
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Administração Cutânea
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Óleos Voláteis
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Medicamentos de Ervas Chinesas
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Farmacocinética
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Química
/
Cromatografia Líquida de Alta Pressão
Limite:
Animals
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2008
Tipo de documento:
Article