Effect of Intravenous Intraoperative Esmolol on Pain Management Following Lower Limb Orthopedic Surgery
The Korean Journal of Pain
; : 198-202, 2015.
Article
em En
| WPRIM
| ID: wpr-28600
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: Lack of proper control of acute postoperative pain often leads to lingering or chronic pain. Several studies have emphasized the role of beta-blockers in reducing postoperative pain. Esmolol is a selective short-acting beta-blocker that produces few side effects. The purpose of this study was to examine the effect of intravenous intraoperative esmolol on postoperative pain reduction following orthopedic leg fracture surgery. METHODS: In a clinical trial, 82 patients between 20-65 years of age with tibia fractures and American Society of Anesthesiologists (ASA) physical status I & II who underwent surgery were divided into two groups. Group A received esmolol and group B received normal saline. Postoperative pain was measured at three time points: entering the recovery unit, and at 3 h and 6 h following surgery, using the Visual Analogue Scale (VAS). A P value of < 0.05 was considered significant. RESULTS: Mean VAS scores at all three time points were significantly different between the two test groups (P = 0.02, P = 0.0001, and P = 0.0001, respectively). The consumption of pethidine was lower in group A than in group B (P = 0.004) and the duration of its effect was significantly longer in time (P = 0.026). CONCLUSIONS: Intravenous intraoperative esmolol is effective in the reduction of postoperative pain following leg fracture surgery. It reduced opioid consumption following surgery and delayed patient requests for analgesics.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Ortopedia
/
Dor Pós-Operatória
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Tíbia
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Fraturas da Tíbia
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Medição da Dor
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Extremidade Inferior
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Dor Crônica
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Manejo da Dor
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Escala Visual Analógica
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Analgésicos
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Revista:
The Korean Journal of Pain
Ano de publicação:
2015
Tipo de documento:
Article