Progress of molecular genetics research on rheumatoid arthritis / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 728-733, 2015.
Article
em Zh
| WPRIM
| ID: wpr-287999
Biblioteca responsável:
WPRO
ABSTRACT
Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disorder that principally attacks flexible joints and synovia. The precise pathogenesis of RA remains unclear, and genetic factors probably play an important role in its etiology. In addition to genes from human leukocyte antigen (HLA) region, such as HLA-DRB, genes from non-HLA region, such as TIM-3, PTPN22, TRAF1/C5, STAT4, CCR5, PADI4 and FCGR2A may also contribute to its susceptibility. The advance in molecular genetics research on RA is reviewed here.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Artrite Reumatoide
/
Receptores de IgG
/
Predisposição Genética para Doença
/
Proteína Tirosina Fosfatase não Receptora Tipo 22
/
Cadeias HLA-DRB1
/
Exoma
/
Receptor Celular 2 do Vírus da Hepatite A
/
Genética
/
Proteínas de Membrana
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2015
Tipo de documento:
Article