Expression of trophinin in human oocytes and preimplantation embryos / 南方医科大学学报
Journal of Southern Medical University
; (12): 122-124, 2008.
Article
em Zh
| WPRIM
| ID: wpr-293437
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the significance of trophinin expression in human oocytes and preimplantation embryos.</p><p><b>METHODS</b>The expression of trophinin in 9 human oocytes, 16 blastomeres and 12 blastocysts were detected by indirect immunofluorescence assay and observed under laser scanning confocal microscope.</p><p><b>RESULTS</b>Human oocytes, blastomeres and blastocysts were all positive for trophinin expression, and the positivity intensified significantly in the course of the embryonic development (P<0.05).</p><p><b>CONCLUSION</b>Trophinin may play an important role in human embryo implantation by mediating homophilic adhesion between the embryo and the endometrium during the implantation window.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Oócitos
/
Blastocisto
/
Moléculas de Adesão Celular
/
Microscopia Confocal
/
Técnica Indireta de Fluorescência para Anticorpo
/
Metabolismo
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
Zh
Revista:
Journal of Southern Medical University
Ano de publicação:
2008
Tipo de documento:
Article