Study on chemical constituents in roots and rhizomes of Ligularia duciforms II / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents in roots and rhizomes of Ligularia duciforms.</p><p><b>METHOD</b>90% ethanol extract was isolated and purified by silica gel and sephadex LH-20 column chromatography, the structures of compounds were identified by physicochemical properties and spectral analysis.</p><p><b>RESULT</b>Nine compounds were isolated and identified as lupeol (1), isoscopoletin (2), isoline (3), duciformine (4), (2S, 3S, 4R)-sphinganine-(2'R)-delta5',6' (E)-2'-hydroxytetracosanoylamino (5), tetracosanoic acid (6), tetracosanoicacid glyceride (7), (E)-docosyl ferulate (8), (E)-docosyl caffeate (9).</p><p><b>CONCLUSION</b>Compounds 1, 2, 5-7 were isolated for the first time from this plant, and the compound 2, 5-7 were isolated firstly from the genus Ligularia.</p>