Optimizing extraction process of Scutellaria barbata by golden section method / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To probe into the feasibility of golden section method in the optimization of the extraction process of Scutellaria barbata.</p><p><b>METHOD</b>With the determination of the content of scutellarin and total flavonoids, selecting the range of alcohol concentration in the extraction of S. barbata was determined by the golden section method and method of equal interval, and validated it by orthogonal design.</p><p><b>RESULT</b>The best extraction technique is that extract 3 times with 15 times of the alcohol which concentration is 70%, and each time for 1 h.</p><p><b>CONCLUSION</b>Applying golden section method in the extraction of S. barbata is practical, which as a method of preliminary trial, indicates that golden section method can also be applied into the field of optimization of extraction process of traditional Chinese medicine.</p>