Identification and expression of non-coding RNAs NC28 and NC119 in human tumors / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 618-621, 2007.
Article
em Zh
| WPRIM
| ID: wpr-298771
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore and identify the non-coding RNAs related to tumors.</p><p><b>METHODS</b>We used RT-PCR and Northern blot to analyze non-coding RNAs in tumor tissues and cell lines.</p><p><b>RESULTS</b>Two predicted non-coding RNAs were confirmed to be expressed in cancer tissues and cell lines by RT-PCR and DNA sequencing. We detected the expression of two non-coding RNA transcripts by Northern blot. The length of NC28 was about 1800 nt, and that of NC119 was about 1200nt.</p><p><b>CONCLUSIONS</b>NC28 and NC119 have a tumor-associated expression pattern. The non-coding RNAs may play a role in the development of tumors.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
RNA não Traduzido
/
Linhagem Celular Tumoral
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Metabolismo
/
Neoplasias
Limite:
Humans
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2007
Tipo de documento:
Article