Research progresses in the pathogenesis, diagnosis and treatment of infantile hemangioma with PHACE syndrome / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 1291-1296, 2017.
Article
em Zh
| WPRIM
| ID: wpr-300405
Biblioteca responsável:
WPRO
ABSTRACT
Infant hemangioma, the most common benign tumor in children, is characterized by rapid proliferation, followed by slower spontaneous involution. However, some patients with facial segmental hemangioma are associated with PHACE syndrome. PHACE syndrome is characterized by vascular nerve and vascular cutaneous lesions of multiple systemic systems, often resulting in structural and functional impairments. Recent studies have demonstrated that the possible pathogeneses of PHACE syndrome mainly include hypoxia, abnormality of mesodermal vascular endothelial cells, genetic abnormality, and abnormality of interstitial mesenchymal stem cells. The current medications for hemangioma with PHACE syndrome include beta blockers, glucocorticoids, and mTOR inhibitors. This review article mainly describes the pathogenesis, diagnoses and treatments of PHACE syndrome, in order to provide directions for diagnosis and treatment of this disorder.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Terapêutica
/
Anormalidades Múltiplas
/
Anormalidades do Olho
/
Diagnóstico
/
Cardiopatias Congênitas
/
Hemangioma
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
/
Infant
Idioma:
Zh
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2017
Tipo de documento:
Article