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Updated Relationship of microRNA with male reproduction / 中华男科学杂志
National Journal of Andrology ; (12): 963-966, 2015.
Article em Zh | WPRIM | ID: wpr-304790
Biblioteca responsável: WPRO
ABSTRACT
Spermatogenesis is a unique process of cell differentiation, which involves the regulation of a series of complicated post-transcriptional expressions. MicroRNAs (miRNAs) are a class of none-coding RNAs that play important roles in regulating post-transcriptional gene silencing. MiRNAs are expressed in a cell-specific manner in spermatogenesis and participate in the maturation and differentiation of male germ cells. The specifically altered seminal plasma miRNA is closely related with spermatogenic dysfunction and therefore can be used as a novel biomarker for the diagnosis of male infertility. A deeper insight into these specific miRNAs may point a new direction in the studies of the molecular mechanisms of spermatogenesis and spermatogenic dysfunction.
Assuntos
Texto completo: 1 Índice: WPRIM Assunto principal: Fisiologia / Sêmen / Espermatogênese / Biomarcadores / Diferenciação Celular / MicroRNAs / Interferência de RNA / Genética / Genitália Masculina / Células Germinativas Limite: Humans / Male Idioma: Zh Revista: National Journal of Andrology Ano de publicação: 2015 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Fisiologia / Sêmen / Espermatogênese / Biomarcadores / Diferenciação Celular / MicroRNAs / Interferência de RNA / Genética / Genitália Masculina / Células Germinativas Limite: Humans / Male Idioma: Zh Revista: National Journal of Andrology Ano de publicação: 2015 Tipo de documento: Article