Primary testicular yolk sac tumor: clinicopathological study of 8 cases / 中华男科学杂志
National Journal of Andrology
; (12): 435-438, 2014.
Article
em Zh
| WPRIM
| ID: wpr-309693
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinicopathological characteristics, diagnosis and treatment of primary testicular yolk sac tumor (YST).</p><p><b>METHODS</b>We studied 8 cases of primary testicular YST by microscopy and immunohistochemistry.</p><p><b>RESULTS</b>The 8 cases of primary testicular YST, including 2 consultation cases, were confirmed from 1998 to 2013, accounting for 10.7% (8/75) of all the testicular germ cell tumors diagnosed in our hospital. The patients ranged in age from 7 to 43 years, 23.9 years on average. The main clinical manifestation of the patients was painless unilateral testis swelling. Microscopically, reticular tissues, schiller-duvaI (S-D) bodies, and eosin-stain transparent bodies were seen in the tumors. One of the cases was confirmed to be simple YST, while the other 7 mixed YST. AFP was a characteristic immunophenotype marker of the tumors.</p><p><b>CONCLUSION</b>Primary testicular YST is a rare malignancyr with poor prognosis. Its diagnosis depends on preoperative AFP test and postoperative pathology. Comprehensive treatment, including orchiectomy, chemotherapy, and radiotherapy, can prolong the survival of the patients.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Patologia
/
Neoplasias Testiculares
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Terapêutica
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Imuno-Histoquímica
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Orquiectomia
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Tumor do Seio Endodérmico
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Neoplasias Embrionárias de Células Germinativas
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Doenças Raras
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Metabolismo
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
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Adult
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Child
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Humans
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Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2014
Tipo de documento:
Article