The effect of Gynostemma pentaphyllum (GP) on plasma lipoprotein metabolism and lipoperoxidation lipoprotein in the experimental hyperglycemia rats / 中国应用生理学杂志
Chinese Journal of Applied Physiology
; (6): 205-208, 2008.
Article
em Zh
| WPRIM
| ID: wpr-310765
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>AIM</b>To study the regulation mechanism of GP on plasma lipoprotein metabolism and To explore its mechanism of anti-lipoperoxidation in the experimental hyperglycemia rats.</p><p><b>METHODS</b>The rats were raised with high fat diet for six weeks,and the model of hyperglycemia was then established. After that, those rats were treated with high or low dose of GP and xuezhikang as a masculine comparison for four weeks. Then, those rat were executed, and detected the plasma TC, TG, LDL-C, HDL-C, GSH-Px, at the same time the SOD, CAT and MDA concentration also be mensurated.</p><p><b>RESULTS</b>The results showed that high and low dose of GP could decrease the concentration of serum LDL-C, cholesterol and triglyceride remarkably and raise the concentration of HDL-C. The activity of GSH-Px, SOD and CAT in GP groups were promoted and the level of MDA was decreased distinctly.</p><p><b>CONCLUSION</b>The GP can therapy the abnormity of serum lipid and has obviously anti-lipoperoxidation affection.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Triglicerídeos
/
Sangue
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Extratos Vegetais
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Peroxidação de Lipídeos
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Colesterol
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Ratos Wistar
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Gynostemma
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Usos Terapêuticos
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Tratamento Farmacológico
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Hiperlipidemias
Limite:
Animals
Idioma:
Zh
Revista:
Chinese Journal of Applied Physiology
Ano de publicação:
2008
Tipo de documento:
Article