Risk Factors and the Clinical Course of Acute Kidney Injury in Patients with a Femoral Fracture / 대한내과학회지
Korean Journal of Medicine
; : 818-826, 2013.
Article
em Ko
| WPRIM
| ID: wpr-32702
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS:
Femoral fracture occurs most often in elderly patients and is highly associated with medical problems such as acute kidney injury (AKI); however no reports of AKI in femoral fracture patients have been published. This study was performed to identify risk factors and the clinical course of AKI in patients with femoral fracture.METHODS:
We retrospectively evaluated the medical records of 110 patients with femoral fracture between November 2006 and December 2011 at Uijeongbu St. Mary's Hospital. We investigated the incidence and clinical course of AKI in femoral fracture patients and compared the clinical findings between AKI and normal kidney function (NKF) groups.RESULTS:
Of the 110 femoral fracture patients, AKI was observed in 19 (17.3%). The peak serum creatinine level in patients with AKI was 2.59 +/- 1.57 mg/dL. Two of 19 patients with AKI died and two progressed to chronic kidney disease. When compared to the NKF group, the AKI group had a higher incidence of elevated lactate dehydrogenase (LDH) (63.2% vs. 34.1%, p = 0.020), erythrocyte sedimentation rate (ESR) (31.6% vs. 6.6%, p = 0.008), and C-reactive protein (57.9% vs. 46.2%, p = 0.042). The AKI group also had a longer hospitalization duration, and more patients were prescribed an angiotensin-converting-enzyme (ACE) inhibitor than in the NKF group. Multivariate analysis demonstrated elevated LDH, ESR and ACE inhibitor prescriptions as independent risk factors for AKI in patients with a femoral fracture.CONCLUSIONS:
The incidence of AKI in patients with a femoral fracture was 17.3%, and AKI was associated with a longer clinical course. We recommend monitoring of laboratory findings and medications and early management to reduce the morbidity of patients with AKI.Palavras-chave
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Índice:
WPRIM
Assunto principal:
Sedimentação Sanguínea
/
Proteína C-Reativa
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Prontuários Médicos
/
Incidência
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Análise Multivariada
/
Estudos Retrospectivos
/
Fatores de Risco
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Creatinina
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Insuficiência Renal Crônica
/
Prescrições
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2013
Tipo de documento:
Article