Effect of finasteride on intraoperative bleeding and irrigating fluid absorption during transurethral resection of prostate: a quantitative study / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 258-260, 2004.
Article
em Zh
| WPRIM
| ID: wpr-341894
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of pretreatment with finasteride in decreasing intraoperative bleeding and irrigating fluid absorption during transurethral resection of prostate (TURP).</p><p><b>METHODS</b>Eighty patients with benign prostate hypertrophy undergoing TURP were divided into two groups: 40 patients were pretreated with finasteride for 7 to 14 days before TURP and 40 patients without pretreatment. Absorption of irrigating fluid was quantified by analyzing the serum concentration of gentamycin. Intraoperative blood loss was calculated based on hemoglobin concentrations before and after operation.</p><p><b>RESULT</b>The whole blood loss, hemoglobin concentration of irrigating fluid used, blood loss per minute, blood loss per gram tissue resected, whole irrigation absorption, irrigation absorption per minute and per gram tissue resected in patients pretreated with finasteride were significantly less than those in patients without pretreatment (P<0.05). The blood transfusion volume, the incidence of hypotension and hyponatremia in patients pretreated with finasteride were significantly less than those in patients without pretreatment (P<0.05).</p><p><b>CONCLUSION</b>Pretreatment with finasteride is of value in reducing intraoperative bleeding, irrigation absorption and perioperative complication during TURP.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Hiperplasia Prostática
/
Cirurgia Geral
/
Perda Sanguínea Cirúrgica
/
Finasterida
/
Ressecção Transuretral da Próstata
/
Usos Terapêuticos
/
Absorção
/
Complicações Intraoperatórias
/
Irrigação Terapêutica
Limite:
Aged
/
Humans
/
Male
Idioma:
Zh
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2004
Tipo de documento:
Article