Progress in genetic research on psoriatic arthritis / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 606-610, 2017.
Article
em Zh
| WPRIM
| ID: wpr-344211
Biblioteca responsável:
WPRO
ABSTRACT
Psoriatic arthritis is a form of inflammatory arthritis found among patients with psoriasis, which can lead to pain, swelling or stiffness in one or more joints and even movement disorders. Epidemiological studies have shown a higher heritability for psoriatic arthritis compared with psoriasis vulgaris. With the evolvement of DNA sequencing, many genes have been associated with psoriasis vulgaris and psoriatic arthritis, which included MHC, TNF, LCE, IL23R, IL12B, TRAF3IP2 and TNFAIP3, though some, such as MHC, IL-13 and PTPN22, have been specifically associated with psoriatic arthritis. These studies have laid a foundation for risk prediction, diagnosis and drug development for psoriatic arthritis.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Psoríase
/
Artrite Psoriásica
/
Predisposição Genética para Doença
/
Polimorfismo de Nucleotídeo Único
/
Pesquisa em Genética
/
Genética
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2017
Tipo de documento:
Article