Low-dose tadalafil for erectile dysfunction following pelvic fracture-induced urethral injury: clinical observation of 42 cases / 中华男科学杂志
National Journal of Andrology
; (12): 539-541, 2013.
Article
em Zh
| WPRIM
| ID: wpr-350864
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy of daily low-dose tadalafil in the treatment of erectile dysfunction (ED) following pelvic fracture-induced urethral injury (PFUI).</p><p><b>METHODS</b>Based on the length of time between pelvic fracture and the patients' clinic visit, we divided 42 PFUI-caused ED patients into groups A (< 1 month), B (6-24 months) and C (> 24 months). We treated them with tadalafil at 5 mg daily for 12 weeks consecutively, followed by evaluation of the therapeutic effect using IIEF-5 questionnaire and Sexual Encounter Profile (SEP) diaries.</p><p><b>RESULTS</b>Thirty-four patients (83.3%) completed the investigation and all responded well to tadalafil medication. Group A showed significant differences from B and C in the increase of IIEF-5 scores and the positive rate of SEP.</p><p><b>CONCLUSION</b>Daily low-dose tadalafil helps penile rehabilitation in ED patients following PFUI, and the earlier the medication is initiated, the better the effect will be.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Pelve
/
Uretra
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Ferimentos e Lesões
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Carbolinas
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Resultado do Tratamento
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Usos Terapêuticos
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Relação Dose-Resposta a Droga
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Tratamento Farmacológico
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Fraturas Ósseas
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Tadalafila
Limite:
Adult
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Humans
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Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2013
Tipo de documento:
Article