Study on the injurious effect of a self designed micro-skin machine on the epithelia / 中华烧伤杂志
Chinese Journal of Burns
; (6): 355-357, 2003.
Article
em Zh
| WPRIM
| ID: wpr-352254
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the injury on micro-skin induced by a self designed micro-skin machine.</p><p><b>METHODS</b>Micro-skin was produced either with the machine or by hand. Cells at the edge of micro-skin were observed by transmission electron microscope. succinic dehydrogenase activity in supernatant of cultivated cells was analyzed, and the cell proliferation of micro-skin was assessed by (3)H-TdR. Twenty patients were enrolled in the study for the observation of the wound healing time between the two groups of micro-skin after being grafted.</p><p><b>RESULTS</b>Transmission electron microscope examination revealed that the cellular injury at the edge of the micro-skin in machine-made group was mild compared with that in man-made group. (3)H-TdR rate was elevated but the activity of succinic dehydrogenase in the supernatant of cultured cells decreased in supernatant of cultured cells of machine produced micro-skin. Wound healing time was shortened in machine made group. (P < 0.05).</p><p><b>CONCLUSION</b>The cellular injury at the edge of micro-skin in the machine made group was mild when compared with that in the man-made group with cell proliferation accelerated and wound healing time shortened.</p>
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Índice:
WPRIM
Assunto principal:
Patologia
/
Pele
/
Cirurgia Geral
/
Cicatrização
/
Queimaduras
/
Microscopia Eletrônica
/
Divisão Celular
/
Transplante de Pele
/
Epitélio
/
Métodos
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Burns
Ano de publicação:
2003
Tipo de documento:
Article