Analysis of B/C recombinant structure of C gene in a newly found HBV subtype / 病毒学报
Chinese Journal of Virology
; (6): 19-24, 2014.
Article
em Zh
| WPRIM
| ID: wpr-356644
Biblioteca responsável:
WPRO
ABSTRACT
Hepatitis B is one of the most serious global threats to human health. Phylogenetic analysis of hepatitis B virus (HBV) can reveal the evolutionary relationship between HBV sequences and thus provide a basis for the prediction and treatment of hepatitis B and other aspects. In this study, we performed sequence analyses on the HBV sequences of five clinical HBV samples and the HBV sequences retrieved from the GenBank, EMBL, and DDBJ to construct a phylogenetic tree and analyze sequence structures. The experimental results revealed that the C gene of one cloned sequence had a recombinant structure of HBV B/ C subtype. Moreover, the phylogenetic results proved the existence of a newly found subtype HBV/B6 in Xishuangbanna of Yunnan Province, China. The experimental conclusion represents certain value for phylogenetic studies of HBV in Yunnan ethnic minority groups.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Filogenia
/
DNA Recombinante
/
Vírus da Hepatite B
/
Classificação
/
Técnicas de Genotipagem
/
Genes Virais
/
Genética
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Virology
Ano de publicação:
2014
Tipo de documento:
Article