Progress in models of pancreatic cancer / 国际外科学杂志
International Journal of Surgery
; (12): 173-176, 2011.
Article
em Zh
| WPRIM
| ID: wpr-414733
Biblioteca responsável:
WPRO
ABSTRACT
Pancreatic cancer is a highly malignant tumor. Animal models of pancreatic cancer included xenograft models, carcinogen induced models, genetically engineered models. Xenograft models are relatively reliable and feasible, but the growth pattern is different between serve immunodeficienct animals and human beings. Carcinogens induced models simulated the environmental factors to reconstruct the development of pancreatic cancer. But carcinogens could have other biological effects. Genetically engineered models could make the occurrence of pancreatic cancer at the molecular level. But it is difficult to control the transgenic product accurately. No model could meet all the needs of different experiments. It is important to choose a suitable animal model in different experiments.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
International Journal of Surgery
Ano de publicação:
2011
Tipo de documento:
Article