Your browser doesn't support javascript.
loading
PCR-based techniques for the detection of minority mutations / 中华检验医学杂志
Article em Zh | WPRIM | ID: wpr-431174
Biblioteca responsável: WPRO
ABSTRACT
With the development of molecular biology and molecular genetics,more attention has been taken to the advanced techniques which can be used to detect minority mutations.In recent years,many techniques such as amplification refractory mutation system,PCR clamping,pyrophosphorolysis-activated polymerization,co-amplification at lower denaturation temperature-PCR and digital PCR have been developed,which will make the hereditary disease diagnosis,cancer detection,noninvasive antenatal diagnosis step into a new stage in the near future.This review presents an overview of the principles,aoolications,advantages and disadvantages of these techniques.
Palavras-chave
Texto completo: 1 Índice: WPRIM Tipo de estudo: Diagnostic_studies Idioma: Zh Revista: Chinese Journal of Laboratory Medicine Ano de publicação: 2013 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Tipo de estudo: Diagnostic_studies Idioma: Zh Revista: Chinese Journal of Laboratory Medicine Ano de publicação: 2013 Tipo de documento: Article