A Case of Minimal Change Disease Treated Successfully with Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus
The Korean Journal of Internal Medicine
; : 470-473, 2011.
Article
em En
| WPRIM
| ID: wpr-46532
Biblioteca responsável:
WPRO
ABSTRACT
The World Health Organization classifies lupus nephritis as class I to V or VI. However, a few cases of minimal change glomerulopathy have been reported in association with systemic lupus erythematosus (SLE). Mycophenolate mofetil has been shown to be effective for treatment of minimal change disease and lupus nephritis. A 24-year-old woman diagnosed with SLE five years prior to presentation complained of a mild generalized edema. The urinalysis showed microscopic hematuria and proteinuria. The assessed amount of total proteinuria was 1,618 mg/24 hours. A renal biopsy demonstrated diffuse fusion of the foot processes of podocytes on electron microscopy. Mycophenolate mofetil was started in addition to the maintenance medications of prednisolone 10 mg/day and hydroxychloroquine 400 mg/day. After six months of treatment, the microscopic hematuria and proteinuria resolved, and the total urine protein decreased to 100 mg/24 hours.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Prednisona
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Antirreumáticos
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Glucocorticoides
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Hidroxicloroquina
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Imunossupressores
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Lúpus Eritematoso Sistêmico
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Ácido Micofenólico
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Nefrose Lipoide
Limite:
Female
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Humans
Idioma:
En
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2011
Tipo de documento:
Article