Roles of Hedgehog signaling in T cell differentiation and development / 国际肿瘤学杂志
Journal of International Oncology
; (12): 813-816, 2014.
Article
em Zh
| WPRIM
| ID: wpr-466608
Biblioteca responsável:
WPRO
ABSTRACT
The production of mature functional T cells requires many signals from the thymus such as Wnt,Notch and Hedgehog,et al.The Hedgehog protein family signals for development,patterning and organogenesis of many tissues during mammalian embryogenesis.In recent years,more and more research groups focus their attention on it because of its relationship between tumors.Abnormal differentiation and development of T cells may cause various immunological diseases and tumors.Illuminating the roles of Hedgehog signaling in T cell differentiation and development can provide a theoretical guide in the treatment of tumor.
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WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2014
Tipo de documento:
Article