Molecular targeted therapy for esophageal cancer / 实用肿瘤学杂志

ABSTRACT

According to the 2012 estimates,esophageal cancer(EC)was the fifth commonly diagnosed cancer and the forth leading cause of cancer -related death .The incidence and mortality rates of EC have been increasing in China .Combined -modality therapy for EC is well accepted , and molecular targeted therapy be-comes a research area.Nowadays,multiple agents have been developed and studied in phase Ⅱ/Ⅲtrials,mainly including cetuximab,erlotinib,trastuzumab,bevacizumab.In this review,we focus on the development of molecular targeted therapy for EC .