Optimization of the Separation and Purification Process of Astragaloside Ⅳ by Orthogonal Experiment / 中国药房
China Pharmacy
; (12)2005.
Article
em Zh
| WPRIM
| ID: wpr-530892
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:To optimize the technologic conditions for separation and purification process of Astragaloside Ⅳ using macroreticular resins.METHODS:The optimal extraction process and purification technology using macroreticular resins were investigated by orthogonal experiment design with extract yield and content of Astragaloside Ⅳ as evaluation indexes,and the influencing factors were also investigated.RESULTS:The optimal conditions for extraction were as follows:sixfold amount of water was added to extract Astragaloside Ⅳ for 3 times with 1 h each time.The isolation and purification of Astragaloside Ⅳ were influenced by relative density,elution dosage and velocity.CONCLUSION:The established optimal technologic conditions for the extraction,separation and purification of Astragaloside Ⅳ using macroreticular resins proved to be feasible.
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Índice:
WPRIM
Idioma:
Zh
Revista:
China Pharmacy
Ano de publicação:
2005
Tipo de documento:
Article