STRUCTURAL PROPERTIES OF THE LIPID A COMPONENT OF THE LIPOPOLYSACCHARIDE (ENDOTOXIN) ISOLATED FROM BACTERIODES FRAGILIS NCTC 9343 / 第二军医大学学报
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WPRO
ABSTRACT
Various chemical and gas-liquid chromatographic analyses indicate that the lipid A backbone of the lipopolysaccharide (LPS) isolated from Bacteriodes fragilis NCTC 9343 is chemically constituted by a ?1, 6-interlinked D-gluco-samine disaccharide. It is phosphorylated at its 1-position by a glycosidic-linkage while the ester-bound phosphate present generally in other lipid A is depleted. The lipid A is lower fatty acylated in the amount of 5.2 fatty acids per lipid A molecule (of which 0.73 forms 3-acyloxyacyl groups). The LPS containing such a lipid A component has been shown endowing with a weaker endotoxicity.
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WPRIM
Idioma:
Zh
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
1985
Tipo de documento:
Article