Successful Xenograft of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Specimen from Human Extrahepatic Cholangiocarcinoma into an Immunodeficient Mouse
Gut and Liver
; : 805-808, 2015.
Article
em En
| WPRIM
| ID: wpr-55055
Biblioteca responsável:
WPRO
ABSTRACT
Patient-derived tumor xenograft is the transfer of primary human tumors directly into an immunodeficient mouse. Patient-derived tumor xenograft plays an important role in the development and evaluation of new chemotherapeutic agents. We succeeded in generating a patient-derived tumor xenograft of a biliary tumor obtained by endoscopic ultrasound-guided fine-needle aspiration from a patient who had an inoperable extrahepatic cholangiocarcinoma. This patient-derived tumor xenograft will be a promising tool for individualized cancer therapy and can be used in developing new chemotherapeutic agents for the treatment of biliary cancer in the future.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Transplante Heterólogo
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Neoplasias dos Ductos Biliares
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Colangiocarcinoma
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Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico
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Xenoenxertos
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Camundongos Nus
Limite:
Animals
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Humans
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Male
Idioma:
En
Revista:
Gut and Liver
Ano de publicação:
2015
Tipo de documento:
Article