Study on the Quality Standard of Gentiana scabra Dispensing Granule / 中国药房
China Pharmacy
; (12): 2097-2098,2099, 2016.
Article
em Zh
| WPRIM
| ID: wpr-605667
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To establish the quality standard for Gentiana scabra dispensing granule.METHODS:
TLC was ad-opted to identify G. scabra in the preparation;HPLC was adopted to determine the content of gentiopicroside in the preparationthe column was Dionex C18 with mobile phase of methanol- water(25∶75,V/V)at a flow rate of 1.0 ml/min,the detection wave-length was 270 nm,column temperature was 30 ℃,the injection volume was 10 μl.RESULTS:
TLC showed clear spots and good separation. The linear range of gentiopicroside injection volume was 0.302 6-3.026 μg (r=0.999 9);RSDs of precision,stability and reproducibility tests were lower than 2%;recovery was 98.27%-99.56%(RSD=0.68%,n=6).CONCLUSIONS:
The estab-lished standard can be used for the quality control of Gentiana scabra dispensing granule.
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Índice:
WPRIM
Idioma:
Zh
Revista:
China Pharmacy
Ano de publicação:
2016
Tipo de documento:
Article